Lauren D. Black III focuses on understanding the biophysical signaling mechanisms responsible for the development of healthy and diseased myocardium including mechanical stress/strain, electrical stimulation, and cell-cell/ cell-matrix interactions. The ultimate goal of his research is to design and develop new methods for repairing diseased or damaged myocardium. To achieve this aim, his group uses novel methods, including whole organ decellularization, mass-spectrometry based proteomics, and non-linear microscopy to study the role that the local extracellular environment plays in normal and pathological cardiac development. These findings are then utilized to develop better tissue engineering scaffolds for both cardiac repair and the development of in vitro disease models. His group has begun to identify specific bioactive fragments of the extracellular matrix that promote beneficial functions in tissue healing and repair. His research has been supported by the National Institutes of Health, the National Science Foundation, the American Heart Association and the Department of Defense. He was the recipient of the Tissue Engineering and Regenerative Medicine International Society (TERMIS)–Americas Chapter Young Investigator Award in 2015.
- Lauren Black, PhD
- Institution: Tufts University
- Associate Professor, Department of Biomedical Engineering
- Research Interests: Design and development of new methods for repairing diseased or damaged myocardium